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CHN2 抗体

CHN2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463475
发货至: 中国
  • 抗原 See all CHN2 抗体
    CHN2 (Chimerin (Chimaerin) 2 (CHN2))
    适用
    • 26
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This CHN2 antibody is un-conjugated
    应用范围
    • 22
    • 19
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHN2.
    Top Product
    Discover our top product CHN2 Primary Antibody
  • 应用备注
    CHN2 antibody can be used for detection of CHN2 by ELISA at 1:62500. CHN2 antibody can be used for detection of CHN2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHN2 antibody at -20 °C.
  • 抗原
    CHN2 (Chimerin (Chimaerin) 2 (CHN2))
    别名
    CHN2 (CHN2 产品)
    别名
    1700026N20Rik antibody, 4930557O16Rik antibody, ARHGAP3 antibody, Bch antibody, BCH antibody, CHN2-3 antibody, RHOGAP3 antibody, chimerin 2 antibody, chimerin 2 L homeolog antibody, chn2 antibody, CHN2 antibody, Chn2 antibody, chn2.L antibody
    背景
    CHN2 is a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. CHN2 plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men.This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    分子量
    38 kDa
    基因ID
    1124
    NCBI登录号
    NP_001035025
    UniProt
    P52757
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