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PILRA 抗体

PILRA 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463032
发货至: 中国
  • 抗原 See all PILRA 抗体
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    适用
    • 12
    • 1
    宿主
    • 8
    • 3
    • 1
    • 1
    克隆类型
    • 10
    • 3
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    This PILRA antibody is un-conjugated
    应用范围
    • 7
    • 7
    • 1
    • 1
    ELISA, Western Blotting (WB)
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PILRA.
    Top Product
    Discover our top product PILRA Primary Antibody
  • 应用备注
    PILRA antibody can be used for detection of PILRA by ELISA at 1:1562500. PILRA antibody can be used for detection of PILRA by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PILRA antibody at -20 °C.
  • 抗原
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    别名
    PILRA (PILRA 产品)
    别名
    PILRA antibody, FDF03 antibody, AV021745 antibody, RGD1562847 antibody, paired immunoglobin like type 2 receptor alpha antibody, paired immunoglobulin-like type 2 receptor alpha antibody, paired immunoglobin-like type 2 receptor alpha antibody, PILRA antibody, LOC489841 antibody, Pilra antibody
    背景
    Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.
    分子量
    18 kDa
    基因ID
    29992
    NCBI登录号
    NP_840057
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