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- 抗原 See all PTPN2 抗体
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTPN2.
- Top Product
- Discover our top product PTPN2 Primary Antibody
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-353) antibody
PTPN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-257) antibodyPTPN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-387) antibodyPTPN2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 201-250) antibodyPTPN2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 马, 犬, Cow, 斑马鱼, 猴, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (C-Term) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-330) antibodyPTPN2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 329-358), (C-Term) antibodyPTPN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33304 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- PTPN2 antibody can be used for detection of PTPN2 by ELISA at 1:312500. PTPN2 antibody can be used for detection of PTPN2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PTPN2 antibody at -20 °C.
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- 抗原
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
- 别名
- PTPN2 (PTPN2 产品)
- 别名
- PTN2 antibody, PTPT antibody, TC-PTP antibody, TCELLPTP antibody, TCPTP antibody, AI325124 antibody, Ptpt antibody, PTP-1B antibody, cb806 antibody, ptpn2 antibody, ptpn2l antibody, wu:fc10h07 antibody, zgc:55339 antibody, zgc:76973 antibody, hm:zeh1546 antibody, zgc:63623 antibody, ptn2 antibody, ptpt antibody, tc-ptp antibody, tcellptp antibody, tcptp antibody, protein tyrosine phosphatase, non-receptor type 2 antibody, protein tyrosine phosphatase, non-receptor type 2 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 2, b antibody, protein tyrosine phosphatase, non-receptor type 2, a antibody, protein tyrosine phosphatase, non-receptor type 2 L homeolog antibody, PTPN2 antibody, Ptpn2 antibody, ptpn2.S antibody, ptpn2b antibody, ptpn2a antibody, ptpn2.L antibody
- 背景
- PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.
- 分子量
- 25 kDa
- 基因ID
- 5771
- UniProt
- P17706
- 途径
- EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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