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UGT1A1 抗体

UGT1A1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462805
发货至: 中国
  • 抗原 See all UGT1A1 抗体
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    适用
    • 48
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    宿主
    • 45
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    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 22
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    This UGT1A1 antibody is un-conjugated
    应用范围
    • 30
    • 22
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UGT1A1.
    Top Product
    Discover our top product UGT1A1 Primary Antibody
  • 应用备注
    UGT1A1 antibody can be used for detection of UGT1A1 by ELISA at 1:1562500. UGT1A1 antibody can be used for detection of UGT1A1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store UGT1A1 antibody at -20 °C.
  • 抗原
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    别名
    UGT1A1 (UGT1A1 产品)
    别名
    BILIQTL1 antibody, GNT1 antibody, HUG-BR1 antibody, UDPGT antibody, UDPGT 1-1 antibody, UGT1 antibody, UGT1A antibody, Gnt1 antibody, UGT1A01 antibody, Udpgt-1a antibody, UgtBr1 antibody, Udpgt antibody, Ugt1 antibody, zgc:123097 antibody, UDP glucuronosyltransferase family 1 member A1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A1 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP-glucuronosyltransferase antibody, UDP-glucuronosyltransferase 1-6 antibody, UDP glucuronosyltransferase 1 family polypeptide a1 antibody, UGT1A1 antibody, Ugt1a1 antibody, LOC100065342 antibody, LOC100125517 antibody, LOC100229734 antibody, LOC100405984 antibody, LOC100511479 antibody, ugt1a1 antibody
    背景
    UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
    分子量
    57 kDa
    基因ID
    54658
    NCBI登录号
    NP_000454
    UniProt
    P22309
    途径
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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