KAT2B 抗体
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北京 101111
Quick Overview for KAT2B 抗体 (ABIN2460477)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCAF.
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应用备注
- PCAF antibody can be used for detection of PCAF by ELISA at 1:62500. PCAF antibody can be used for detection of PCAF by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCAF antibody at -20 °C.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- PCAF
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背景
- CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
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分子量
- 93 kDa
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基因ID
- 8850
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NCBI登录号
- NP_003875
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UniProt
- Q92831
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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