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ELF3 抗体

ELF3 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460403
发货至: 中国
  • 抗原 See all ELF3 抗体
    ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
    适用
    • 64
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    人, 大鼠
    宿主
    • 64
    • 3
    • 1
    • 1
    克隆类型
    • 65
    • 4
    多克隆
    标记
    • 35
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    This ELF3 antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ELF3.
    Top Product
    Discover our top product ELF3 Primary Antibody
  • 应用备注
    ELF3 antibody can be used for detection of ELF3 by ELISA at 1:312500. ELF3 antibody can be used for detection of ELF3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ELF3 antibody at -20 °C.
  • 抗原
    ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
    别名
    ELF3 (ELF3 产品)
    别名
    ert antibody, esx antibody, epr-1 antibody, ese-1 antibody, ESE-1 antibody, ESX antibody, jen antibody, EPR-1 antibody, ERT antibody, E74 like ETS transcription factor 3 antibody, E74-like factor 3 antibody, elf3 antibody, Elf3 antibody, ELF3 antibody
    背景
    ELF3 is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an ETS domain, which is unique in that the 5' half shows relatively weak homology to known ets factors, and an A/T hook domain, found in HMG proteins and various other nuclear factors. In contrast to any known ets factors, ELF3 is expressed exclusively in epithelial cells. ELF3 is expected to be a critical regulator of epithelial cell differentiation. ETS factor ELF3 is a transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation. ELF3 overexpressed early during human breast tumorigenesis. ELF3 expression confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells. ELF3 mediates the expression of TGF-beta RII, and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis. ELF3 is positively and negatively modulated by other interacting proteins including Ku70, Ku86, p300, and CBP.
    分子量
    41 kDa
    基因ID
    1999
    NCBI登录号
    NP_004424
    UniProt
    P78545
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