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- 抗原 See all RAD17 抗体
- RAD17
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAD17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by protein A chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RAD17.
- Top Product
- Discover our top product RAD17 Primary Antibody
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anti-RAD17 (RAD17) (AA 1-584) antibody
RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-110) antibodyRAD17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-RAD17 (RAD17) (AA 391-670) antibodyRAD17 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-270) antibodyRAD17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 621-670) antibodyRAD17 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 3-10E-010 unconjugated
anti-RAD17 (RAD17) (pSer645) antibodyRAD17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- RAD17 antibody can be used for detection of RAD17 by ELISA at 1:62500. RAD17 antibody can be used for detection of RAD17 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RAD17 antibody at -20 °C.
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- 抗原
- RAD17
- 别名
- RAD17 (RAD17 产品)
- 别名
- zgc:91969 antibody, RAD17 antibody, K2A18.21 antibody, K2A18_21 antibody, RADIATION SENSITIVE 17 antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17SP antibody, RAD24 antibody, 9430035O09Rik antibody, MmRad24 antibody, RAD17 checkpoint clamp loader component antibody, Rad17p antibody, RADIATION SENSITIVE 17 antibody, RAD17 antibody, rad17 antibody, ATRAD17 antibody, Rad17 antibody
- 背景
- RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported.
- 分子量
- 66 kDa, 76 kDa, 76 kDa, 77 kDa, 57 kDa, 76 kDa, 76 kDa, 76 kDa
- 基因ID
- 5884
- NCBI登录号
- NP_579919
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