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GLE1 抗体

GLE1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459776
发货至: 中国
  • 抗原 See all GLE1 抗体
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    适用
    • 16
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    • 1
    • 1
    • 1
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    宿主
    • 14
    • 3
    克隆类型
    • 16
    • 1
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    This GLE1 antibody is un-conjugated
    应用范围
    • 12
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLE1.
    Top Product
    Discover our top product GLE1 Primary Antibody
  • 应用备注
    GLE1 antibody can be used for detection of GLE1 by ELISA at 1:1562500. GLE1 antibody can be used for detection of GLE1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store GLE1 antibody at -20 °C.
  • 抗原
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    别名
    GLE1 (GLE1 产品)
    别名
    Dmel\\CG14749 antibody, GLE1 antibody, GLE1L antibody, LCCS antibody, LCCS1 antibody, hGLE1 antibody, Gle1l antibody, 4933405K21Rik antibody, AA553313 antibody, CG14749 gene product from transcript CG14749-RA antibody, nucleoporin GLE1 antibody, RNA export factor Gle1 antibody, GLE1, RNA export mediator antibody, GLE1 RNA export mediator antibody, GLE1 RNA export mediator (yeast) antibody, CG14749 antibody, CpipJ_CPIJ014147 antibody, SJAG_03847 antibody, GLE1 antibody, Gle1 antibody
    背景
    GLE1 is a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    75 kDa
    基因ID
    2733
    NCBI登录号
    NP_001490
    UniProt
    Q53GS7
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