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STING/TMEM173 抗体

TMEM173 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459160
发货至: 中国
  • 抗原 See all STING/TMEM173 (TMEM173) 抗体
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This STING/TMEM173 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM173.
    Top Product
    Discover our top product TMEM173 Primary Antibody
  • 应用备注
    TMEM173 antibody can be used for detection of TMEM173 by ELISA at 1:62500. TMEM173 antibody can be used for detection of TMEM173 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMEM173 antibody at -20 °C.
  • 抗原
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    别名
    TMEM173 (TMEM173 产品)
    别名
    ERIS antibody, MITA antibody, MPYS antibody, NET23 antibody, STING antibody, 2610307O08Rik antibody, Mita antibody, RGD1562552 antibody, transmembrane protein 173 antibody, TMEM173 antibody, Tmem173 antibody
    背景
    TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
    分子量
    42 kDa
    基因ID
    340061
    NCBI登录号
    NP_938023
    UniProt
    Q86WV6
    途径
    Activation of Innate immune Response
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