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NR0B2 抗体

NR0B2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458948
发货至: 中国
  • 抗原 See all NR0B2 抗体
    NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
    适用
    • 49
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    宿主
    • 42
    • 9
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 36
    • 3
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    • 2
    • 1
    • 1
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    This NR0B2 antibody is un-conjugated
    应用范围
    • 35
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR0B2.
    Top Product
    Discover our top product NR0B2 Primary Antibody
  • 应用备注
    NR0B2 antibody can be used for detection of NR0B2 by ELISA at 1:312500. NR0B2 antibody can be used for detection of NR0B2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR0B2 antibody at -20 °C.
  • 抗原
    NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
    别名
    NR0B2 (NR0B2 产品)
    别名
    SHP antibody, SHP1 antibody, SHP-1 antibody, Shp1 antibody, Shp antibody, NR0B2-A antibody, Nr0b2 antibody, SHP-A antibody, gb:bc058069 antibody, nuclear receptor subfamily 0 group B member 2 antibody, nuclear receptor subfamily 0, group B, member 2 antibody, nuclear receptor subfamily 0, group B, member 2a antibody, NR0B2 antibody, Nr0b2 antibody, nr0b2a antibody
    背景
    NR0B2 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    分子量
    28 kDa
    基因ID
    8431
    NCBI登录号
    NP_068804
    UniProt
    Q15466
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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