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- 抗原 See all HAAO 抗体
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HAAO antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAAO.
- Top Product
- Discover our top product HAAO Primary Antibody
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anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 153-223) antibody
HAAO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) antibodyHAAO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) antibodyHAAO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 101-200) antibodyHAAO 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 72-121) antibodyHAAO 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (N-Term) antibodyHAAO 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- HAAO antibody can be used for detection of HAAO by ELISA at 1:312500. HAAO antibody can be used for detection of HAAO by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store HAAO antibody at -20 °C.
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- 抗原
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- 别名
- HAAO (HAAO 产品)
- 别名
- Afu2g17450 antibody, 0610007K21Rik antibody, 0610012J07Rik antibody, 3-HAO antibody, 3-HAOxase antibody, 3HAO antibody, zgc:103585 antibody, HAO antibody, 3-hydroxyanthranilate 3,4-dioxygenase antibody, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog antibody, SPO1774 antibody, CNB05620 antibody, AFUA_2G17450 antibody, Bcep18194_C7641 antibody, Kfla_5491 antibody, Micau_4935 antibody, RBRH_03005 antibody, Krodi_1278 antibody, haao antibody, HAAO antibody, Haao antibody, haao.L antibody
- 背景
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
- 分子量
- 32 kDa
- 基因ID
- 23498
- NCBI登录号
- NP_036337
- UniProt
- P46952
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