RAD51
适用: 人, 大鼠
WB, ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
1) Western blotting: 1,000~5,000 fold dilution 2) Immunoprecipitation 3) Detection of foci formation by indirect immunofluorescence method
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
100 mM NaCl, 20 mM phosphate buffer ( pH 7.4), 50 % glycerol
储存液
Azide free
储存条件
-20 °C
抗原
RAD51
(DNA Repair Protein Homolog 1 (RAD51))
别名
Rad51
背景
Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs, Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.