RAD51 抗体
Our Local Distributor
北京 101111
Quick Overview for RAD51 抗体 (ABIN2452093)
抗原
See all RAD51 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 大鼠, 小鸡
-
纯化方法
- Purified
-
亚型
- IgY
-
-
-
-
应用备注
-
1) Western blotting: 1,000~5,000 fold dilution
2) Immunoprecipitation
3) Detection of foci formation by indirect immunofluorescence method -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 100 mM NaCl, 20 mM phosphate buffer ( pH 7.4), 50 % glycerol
-
储存液
- Azide free
-
储存条件
- -20 °C
-
-
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
-
别名
- Rad51
-
背景
- Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs, Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.
-
UniProt
- Q06609
-
途径
- DNA Damage Repair
抗原
-