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Lamin A/C 抗体 (N-Term)

This 小鼠 单克隆 anti-Lamin A/C antibody specifically detects Lamin A/C in WB, IF 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN228720
发货至: 中国
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Quick Overview for Lamin A/C 抗体 (N-Term) (ABIN228720)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠, 大鼠

宿主

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  • 42
  • 2
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小鼠

克隆类型

  • 106
  • 84
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    Detects endogenous levels of the small fragment of lamin A when cleaved by caspase-6 at Asp230. It is a marker of caspase-6 activity. Detects the small fragment of lamin A/C only when cleaved at Asp230. Does not cross-react with full length lamin A (nor with lamin C). Species cross-reactivity: Mouse and rat.

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to N-terminal residues adjacent to Asp230 in human lamin A.

    Type of Immunogen: Synthetic peptide

    亚型

    IgG1
  • 应用备注

    Approved: ICC, IF (1:1000), WB (1:1000)

    Usage: Western Blot: 1:1000. Immunocytochemistry (ABC) 1:1000. Immunocytochemistry (IF) 1:1000.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol, 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    Lamin A/C (LMNA)

    别名

    LMNA / Lamin A/C

    背景

    Name/Gene ID: LMNA

    Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

    This antibody detects: LMNA / Lamin A+C

    基因ID

    4000

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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