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C5 抗体

C5 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2192166
发货至: 中国
  • 抗原 See all C5 抗体
    C5 (Complement Component 5 (C5))
    适用
    • 124
    • 32
    • 19
    • 16
    • 2
    • 2
    • 2
    小鼠
    宿主
    • 113
    • 15
    • 6
    • 4
    克隆类型
    • 123
    • 14
    多克隆
    标记
    • 49
    • 13
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    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
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    • 1
    This C5 antibody is un-conjugated
    应用范围
    • 69
    • 50
    • 42
    • 39
    • 26
    • 20
    • 12
    • 9
    • 7
    • 7
    • 5
    • 5
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    过滤
    0.2 μm filtered
    Top Product
    Discover our top product C5 Primary Antibody
  • 应用备注
    For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • 抗原
    C5 (Complement Component 5 (C5))
    Abstract
    C5 产品
    别名
    C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
    背景
    C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-alpha, IL-1beta, IL-6 and IL-8. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.
    途径
    Complement System, Carbohydrate Homeostasis
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