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IL-6 抗体

This anti-IL-6 antibody is a 兔 多克隆 antibody detecting IL-6 in WB, Neut 和 IA. Suitable for 小鼠.
产品编号 ABIN2192164
发货至: 中国

Quick Overview for IL-6 抗体 (ABIN2192164)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Neutralization (Neut), Immunoassay (IA)
  • 过滤

    0.2 μm filtered
  • 应用备注

    For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-6 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

    有效期

    12 months
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    背景

    The antibody reacts with natural and recombinant mouse interleukin 6 (IL-6) as assessed by ELISA. The antibody inhibits the biological activity of natural and recombinant mouse IL-6 as determined with the B9 cell bio-assay. The antibody cross-reacts with natural rat IL-6. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas.

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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