(4 references)-
- 抗原 See all IL-6 (IL6) 抗体
- IL-6 (IL6) (Interleukin 6 (IL6))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This IL-6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Neutralization (Neut), Immunoassay (IA), Detection (D)
- 过滤
- 0.2 μm filtered
- 克隆位点
- MP5-32C11
- Top Product
- Discover our top product IL6 Primary Antibody
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anti-Interleukin 6 (IL6) (AA 111-150) antibody
IL6 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) antibodyIL6 适用: 人 ELISA, FACS, Func, ELISpot 宿主: 小鼠 Monoclonal B-E8 unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Interleukin 6 (IL6) (AA 27-212) antibodyIL6 适用: 猕猴 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 18# unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Interleukin 6 (IL6) (AA 101-150) antibodyIL6 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 27-241) antibodyIL6 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C305 unconjugated
anti-Interleukin 6 (IL6) (AA 25-211) antibodyIL6 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 27-55) antibodyIL6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 26-50) antibodyIL6 适用: 人, 大鼠 ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralisation of biological activity dilutions have to be made according to the amount of IL-6 to be inactivated.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin.
- 注意事项
- Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.
- 储存条件
- 4 °C
- 储存方法
- Lyophilized product should be stored at 4 °C Store stock solution in aliquots at -20 °C Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias." in: International journal of cell cloning, Vol. 9, Issue 3, pp. 166-84, (1991) (PubMed).
: "Interleukin-1, interleukin-6: messengers in the neuroendocrine immune system?" in: Pathology, research and practice, Vol. 187, Issue 5, pp. 622-5, (1991) (PubMed).
: "Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 9, pp. 3072-7, (1988) (PubMed).
: "Alloantigen presentation by B cells. Requirement for IL-1 and IL-6." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 9, pp. 2907-11, (1988) (PubMed).
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: "Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias." in: International journal of cell cloning, Vol. 9, Issue 3, pp. 166-84, (1991) (PubMed).
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- 抗原
- IL-6 (IL6) (Interleukin 6 (IL6))
- 别名
- Interleukin 6 (IL6 产品)
- 别名
- BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
- 背景
- The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF- alpha nor does it block human or rat IL-6 in proliferation assays using the KD83 cell line. MP5-32C11 inhibits mouse IL-6-induced proliferation of the NFS60 myelomonocytic cell line and KD83 plasmacytoma. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B- cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody- producing hybridomas.
- 途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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