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GADD34 抗体 (AA 401-500)

PPP1R15A 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2174278
发货至: 中国
  • 抗原 See all GADD34 (PPP1R15A) 抗体
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    抗原表位
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    适用
    • 29
    • 18
    • 17
    • 5
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 2
    • 2
    克隆类型
    • 28
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GADD34 antibody is un-conjugated
    应用范围
    • 30
    • 16
    • 12
    • 12
    • 10
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GADD34
    亚型
    IgG
    Top Product
    Discover our top product PPP1R15A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Yu, Cui, Zong, Gao, Xu, Gao, Chen, Qin, Guan, Liu, Fu, Li, Wang: "The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis." in: The Journal of biological chemistry, Vol. 290, Issue 34, pp. 20687-99, (2015) (PubMed).

  • 抗原
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    别名
    GADD34 (PPP1R15A 产品)
    别名
    9630030H21 antibody, Gadd34 antibody, Myd116 antibody, GADD34 antibody, Peg-3 antibody, RGD1624209 antibody, protein phosphatase 1 regulatory subunit 15A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 15A antibody, protein phosphatase 1, regulatory subunit 15A antibody, PPP1R15A antibody, Ppp1r15a antibody
    背景

    Synonyms: GADD34, Protein phosphatase 1 regulatory subunit 15A, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A

    Background: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

    基因ID
    23645
    UniProt
    O75807
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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