HPV16 E7 抗体 (Middle Region) (Alexa Fluor 555)
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- 抗原 See all HPV16 E7 (HPV-16 E7) 抗体
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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抗原表位
- Middle Region
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适用
- Human Papillomavirus 16 (HPV-16)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HPV16 E7 antibody is conjugated to Alexa Fluor 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- 特异性
- This antibody may also detect HPV35-E7
- 交叉反应
- 人, Virus
- 交叉反应 (详细)
- HPV16
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from middle of HPV16-E7
- 亚型
- IgG
- Top Product
- Discover our top product HPV-16 E7 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
- Abstract
- HPV-16 E7 产品
- 别名
- transforming protein E7 antibody, E7 antibody
- 物质类
- Viral Protein
- 背景
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Synonyms: Protein E7, E7
Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
- 基因ID
- 1489079
- UniProt
- P03129
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