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HPV16 E7 抗体 (Middle Region) (Biotin)

HPV-16 E7 适用: Human Papillomavirus 16 (HPV-16) WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN2173800
发货至: 中国
  • 抗原 See all HPV16 E7 (HPV-16 E7) 抗体
    HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
    抗原表位
    • 11
    • 3
    Middle Region
    适用
    • 29
    • 19
    • 5
    • 4
    Human Papillomavirus 16 (HPV-16)
    宿主
    • 31
    • 10
    克隆类型
    • 31
    • 10
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HPV16 E7 antibody is conjugated to Biotin
    应用范围
    • 40
    • 26
    • 17
    • 13
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody may also detect HPV35-E7
    交叉反应
    人, Virus
    交叉反应 (详细)
    HPV16
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from middle of HPV16-E7
    亚型
    IgG
    Top Product
    Discover our top product HPV-16 E7 Primary Antibody
  • 应用备注
    WB 1:100-1000
    IHC-P 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
    Abstract
    HPV-16 E7 产品
    别名
    transforming protein E7 antibody, E7 antibody
    物质类
    Viral Protein
    背景

    Synonyms: Protein E7, E7

    Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

    基因ID
    1489079
    UniProt
    P03129
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