IL-6 抗体
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北京 101111
Quick Overview for IL-6 抗体 (ABIN208765)
抗原
See all IL-6 (IL6) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with natural and recombinant mouse interleukin 6 (IL-6) as assessed by ELISA. The antibody inhibits the biological activity of natural and recombinant mouse IL-6 as determined with the B9 cell bio-assay. The antibody cross-reacts with natural rat IL-6. IL-6 is a pluripotent 20-22 kD cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis.
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纯化方法
- Purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG
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应用备注
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Approved: Neut, WB (1:10)
Usage: Can be used for Neutralization of mouse and rat IL-6 in bio-assays. Furthermore the antibody is useful for Western Blot and immunoassay. Western Blot: 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-6 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- IL6
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背景
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Name/Gene ID: IL6
Family: Hormone
Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interferon beta-2, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6 -
基因ID
- 3569
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UniProt
- P05231
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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