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CCR3 抗体 (C-Term)

CCR3 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN205726
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 74
    • 30
    • 24
    • 4
    人, 小鼠, 大鼠
    宿主
    • 53
    • 14
    • 5
    • 5
    克隆类型
    • 57
    • 19
    • 1
    多克隆
    标记
    • 39
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR3 antibody is un-conjugated
    应用范围
    • 49
    • 26
    • 26
    • 18
    • 14
    • 13
    • 13
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes human CD193, otherwise known as CC chemokine receptor 3 (CCR3), a seven-helix transmembrane G-protein coupled receptor which, along with and, acts as a principal receptor for the fusion and entry of HIV into target cells. CD193 is expressed by eosinophils, basophils, mast cells, microglia, Th2 helper cells and some epithelial cells. CD193 acts as a receptor for several CC chemokines including monocyte chemoattractant proteins (MCP) -1, -2, -3 and -4, MIP-1a, MIP-1AY, and RANTES. The eotaxin subgroup of CC chemokines act as specific agonists for CD193, and this interaction has become a focus area for studies into the infection of microglia by HIV and allergy research. Has been used successfully for the detection of human CD193 by immunohistochemistry on formalin fixed, paraffin embedded intervertebral disc tissue.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to a 14 amino acid sequence located near human CD193 carboxy-terminus.

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (10 μg/mL), WB (1 μg/mL)

    Usage: Western Blot: LS-C42330 detects a band of approximately 55kD in human spleen cell lysates (predicted MW. 41kD).
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    avoid freeze thaw cycles. Store undiluted.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CCR3 (CCR3 产品)
    别名
    CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
    背景
    Name/Gene ID: CCR3
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CCR3, C-C chemokine receptor type 3, B-chemokine receptor, CD193, CD193 antigen, Chemokine c-c motif receptor 3, C-C chemokine receptor 3, CKR3, CC-CKR-3, CCR-3, CMKBR3, Eosinophil eotaxin receptor, Eotaxin receptor, C-C CKR-3, CC chemokine receptor 3
    基因ID
    1232
    UniProt
    P51677
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