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CD79a 抗体 (AA 208-222) (APC)

Name: CD79a 抗体 (AA 208-222) (APC)
Brand: antibodies-online
SKU: ABIN1981880
Availability: OutOfStock

CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HM47 APC

Flow cytometry analysis (intracellular staining) of CD79a in human peripheral blood with anti-CD79a (HM47) APC. (CD79a 抗体 (AA 208-222) (APC))

FACS

1 image

(7 references)

产品编号 ABIN1981880

发货至: 中国

Datasheet as PDF

抗原 See all CD79a (CD79A) 抗体

CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
抗原表位
69

25

10

10

8

7

7

6

6

5

5

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 208-222
适用
188

97

80

51

50

32

27

25

25

25

15

10

5

4

2

1
人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate
宿主
104

98

1
小鼠
Compatible Secondaries
克隆类型
120

82

1
单克隆
标记
90

18

16

15

13

8

5

5

5

5

5

5

2

1

1

1

1

1

1

1

1

1

1

1
This CD79a antibody is conjugated to APC
应用范围
115

97

64

58

45

25

22

15

10

5

5

3

2

1

1

1

1
Flow Cytometry (FACS)

特异性

The mouse monoclonal antibody HM47 reacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.

交叉反应（详细）

Human, Non-Human Primates, Porcine, Mouse, Rat, Bovine, Canine (Dog), Equine (Horse), Guinea pig, Rabbit, Chicken

纯化方法

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a

克隆位点

HM47

亚型

IgG1 kappa

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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 小鼠 Monoclonal JCB117-HM47-A9 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-145) antibody
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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibody
CD79A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

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CD79A 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal rIGA-764 unconjugated Recombinant Antibody

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (FITC)
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS 宿主: 小鼠 Monoclonal HM57 FITC

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HM57 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal HM47 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (PE)
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS 宿主: 小鼠 Monoclonal HM57 PE

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

说明

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Zhao, Hassan, Perry, Ning, Stass, Dehner: "C-MYC rearrangements are frequent in aggressive mature B-Cell lymphoma with atypical morphology." in: International journal of clinical and experimental pathology, Vol. 1, Issue 1, pp. 65-74, (2008) (PubMed).

Bhargava, Kallakury, Ross, Azumi, Bagg: "CD79a is heterogeneously expressed in neoplastic and normal myeloid precursors and megakaryocytes in an antibody clone-dependent manner." in: American journal of clinical pathology, Vol. 128, Issue 2, pp. 306-13, (2007) (PubMed).

Fernandez, West, Jackson, Kidney: "Immunohistochemical and histochemical stains for differentiating canine cutaneous round cell tumors." in: Veterinary pathology, Vol. 42, Issue 4, pp. 437-45, (2005) (PubMed).

Islas-Ohlmayer, Padgett-Thomas, Domiati-Saad, Melkus, Cravens, Martin, Netto, Garcia: "Experimental infection of NOD/SCID mice reconstituted with human CD34+ cells with Epstein-Barr virus." in: Journal of virology, Vol. 78, Issue 24, pp. 13891-900, (2004) (PubMed).

Torlakovic, Torlakovic: "B-cell markers in lymphocyte predominance Hodgkin disease." in: Archives of pathology & laboratory medicine, Vol. 126, Issue 7, pp. 862-3, (2002) (PubMed).

Rassenti, Kipps: "Expression of Ig-beta (CD79b) by chronic lymphocytic leukemia B cells that lack immunoglobulin heavy-chain allelic exclusion." in: Blood, Vol. 95, Issue 8, pp. 2725-7, (2000) (PubMed).

Mason, Cordell, Tse, van Dongen, van Noesel, Micklem, Pulford, Valensi, Comans-Bitter, Borst: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).
抗原

CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

别名

CD79a (CD79A 产品)

别名

CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody

背景

CD79a molecule,CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.,BCR alpha, Ig-alpha, MB-1, IGA

基因ID

973

UniProt

P11912

途径

BCR Signaling