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PRKAA1 抗体 (Ser485, Ser491)

PRKAA1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197320
发货至: 中国
  • 抗原 See all PRKAA1 抗体
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    抗原表位
    • 30
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    Ser485, Ser491
    适用
    • 154
    • 131
    • 88
    • 27
    • 11
    • 9
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 154
    • 17
    • 1
    克隆类型
    • 143
    • 29
    多克隆
    标记
    • 84
    • 10
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 1
    • 1
    This PRKAA1 antibody is un-conjugated
    应用范围
    • 136
    • 58
    • 45
    • 41
    • 40
    • 38
    • 34
    • 19
    • 13
    • 11
    • 10
    • 3
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of total AMPK1 protein.
    纯化方法
    Immunoaffinity Chromatography using epitope-specific immunogen.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human AMPK1/AMPK2 around the phosphorylation site of serine 485/491 (S-G-Sp-V-S).
    Top Product
    Discover our top product PRKAA1 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    别名
    PRKAA1 (PRKAA1 产品)
    别名
    AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK alpha-1 chain, AMPK1
    基因ID
    5562
    NCBI登录号
    NP_006242
    UniProt
    Q13131
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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