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Cyclin D2 抗体

CCND2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944917
发货至: 中国
  • 抗原 See all Cyclin D2 (CCND2) 抗体
    Cyclin D2 (CCND2)
    适用
    人, 小鼠, 大鼠
    宿主
    • 77
    • 24
    克隆类型
    • 80
    • 21
    多克隆
    标记
    • 51
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cyclin D2 antibody is un-conjugated
    应用范围
    • 77
    • 40
    • 20
    • 17
    • 14
    • 13
    • 13
    • 10
    • 8
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    亚型
    IgG
    Top Product
    Discover our top product CCND2 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Palmero, Holder, Sinclair, Dickson, Peters: "Cyclins D1 and D2 are differentially expressed in human B-lymphoid cell lines." in: Oncogene, Vol. 8, Issue 4, pp. 1049-54, (1993) (PubMed).

    Xiong, Menninger, Beach, Ward: "Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins." in: Genomics, Vol. 13, Issue 3, pp. 575-84, (1992) (PubMed).

  • 抗原
    Cyclin D2 (CCND2)
    别名
    Cyclin D2 (CCND2 产品)
    别名
    si:ch211-240j22.2 antibody, ccnd2 antibody, CCND2 antibody, kiak0002 antibody, zgc:162280 antibody, LOC100224096 antibody, KIAK0002 antibody, BF642806 antibody, C86853 antibody, Vin-1 antibody, Vin1 antibody, cD2 antibody, 2600016F06Rik antibody, AI256817 antibody, cyclin D2, b antibody, cyclin D2 S homeolog antibody, cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, cyclin D2, a antibody, cyclin D2 L homeolog antibody, ccnd2b antibody, ccnd2.S antibody, CCND2 antibody, ccnd2 antibody, ccnd2a antibody, Ccnd2 antibody, ccnd2.L antibody
    背景
    Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
    分子量
    33067 Da
    基因ID
    894
    UniProt
    P30279
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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