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Cyclin D2 抗体 (AA 161-288)

Name: Cyclin D2 抗体 (AA 161-288)
SKU: ABIN738366
Availability: OutOfStock

CCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human flat moss tinea tissue labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated (ABIN738366) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Cyclin D2 抗体 (AA 161-288))

IHC

Formalin-fixed and paraffin embedded rat ovary labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (Cyclin D2 抗体 (AA 161-288))

IHC (p)

Formalin-fixed and paraffin embedded rat ovary labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated (ABIN738366) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (Cyclin D2 抗体 (AA 161-288))

IHC

Image provided by One World Lab validation program. (Cyclin D2 抗体 (AA 161-288))

IF (cc)

Formalin-fixed and paraffin embedded human flat moss tinea tissue labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (Cyclin D2 抗体 (AA 161-288))

IHC (p)

6 images

(1 reference)

产品编号 ABIN738366

发货至: 中国

Datasheet as PDF

抗原 See all Cyclin D2 (CCND2) 抗体

Cyclin D2 (CCND2)
抗原表位
15

15

12

8

7

6

5

5

4

2

2

1

1

1

1

1
AA 161-288

适用

人, 小鼠, 大鼠
宿主
76

24
兔
Compatible Secondaries
克隆类型
79

21
多克隆
标记
50

6

6

5

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This Cyclin D2 antibody is un-conjugated
应用范围
76

39

20

17

13

12

12

10

8

7

3

2

2

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Cyclin D2

亚型

IgG
anti-Cyclin D2 (CCND2) (AA 47-267) antibody
CCND2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 68-278) antibody
CCND2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 215-285) antibody
CCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 189-289) antibody (Biotin)
CCND2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin

anti-Cyclin D2 (CCND2) (AA 189-289) antibody (PE)
CCND2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PE

anti-Cyclin D2 (CCND2) (AA 189-289) antibody (PerCP)
CCND2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PerCP

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Wu, Gao, Chen, Gu, Ding, Guo: "Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest." in: Molecular and cellular endocrinology, Vol. 377, Issue 1-2, pp. 112-22, (2013) (PubMed).
抗原

Cyclin D2 (CCND2)

别名

Cyclin D2 (CCND2 产品)

别名

si:ch211-240j22.2 antibody, ccnd2 antibody, CCND2 antibody, kiak0002 antibody, zgc:162280 antibody, LOC100224096 antibody, KIAK0002 antibody, BF642806 antibody, C86853 antibody, Vin-1 antibody, Vin1 antibody, cD2 antibody, 2600016F06Rik antibody, AI256817 antibody, cyclin D2, b antibody, cyclin D2 S homeolog antibody, cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, cyclin D2, a antibody, cyclin D2 L homeolog antibody, ccnd2b antibody, ccnd2.S antibody, CCND2 antibody, ccnd2 antibody, ccnd2a antibody, Ccnd2 antibody, ccnd2.L antibody

背景

Synonyms: MPPH3, KIAK2, G1/S-specific cyclin-D2, CCND2
Background: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).

基因ID

894

UniProt

P30279

途径

Cell Division Cycle, Mitotic G1-G1/S Phases