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SP1 抗体 (AA 1-250)

SP1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1326CT463-109-176 unconjugated
产品编号 ABIN2838536
发货至: 中国
  • 抗原 See all SP1 抗体
    SP1 (Sp1 Transcription Factor (SP1))
    抗原表位
    • 20
    • 14
    • 12
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-250
    适用
    • 96
    • 64
    • 43
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 97
    • 13
    • 3
    小鼠
    克隆类型
    • 90
    • 23
    单克隆
    标记
    • 68
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
    This SP1 antibody is un-conjugated
    应用范围
    • 91
    • 47
    • 46
    • 38
    • 22
    • 17
    • 14
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This SP1 antibody is generated from a mouse immunized with a recombination protein from the human SP1.
    克隆位点
    1326CT463-109-176
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SP1 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Takahara, Kanazu, Yanagisawa, Akanuma: "Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38067-72, (2000) (PubMed).

    Kadonaga, Carner, Masiarz, Tjian: "Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain." in: Cell, Vol. 51, Issue 6, pp. 1079-90, (1988) (PubMed).

  • 抗原
    SP1 (Sp1 Transcription Factor (SP1))
    别名
    SP1 (SP1 产品)
    别名
    fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
    背景
    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
    分子量
    80693
    基因ID
    6667
    UniProt
    P08047
    途径
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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