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CHRNA9 抗体 (N-Term)

CHRNA9 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB46802 unconjugated
产品编号 ABIN1944733
发货至: 中国
  • 抗原 See all CHRNA9 抗体
    CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 8-42, N-Term
    适用
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 11
    • 1
    克隆类型
    • 11
    • 1
    多克隆
    标记
    • 12
    This CHRNA9 antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-42 amino acids from the N-terminal region of human CHRNA9.
    克隆位点
    RB46802
    亚型
    Ig Fraction
    Top Product
    Discover our top product CHRNA9 Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

    Peng, Ferris, Matthews, Hiel, Lopez-Albaitero, Lustig: "Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes." in: Life sciences, Vol. 76, Issue 3, pp. 263-80, (2004) (PubMed).

    Lustig, Peng: "Chromosome location and characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) gene." in: Cytogenetic and genome research, Vol. 98, Issue 2-3, pp. 154-9, (2003) (PubMed).

    Sgard, Charpantier, Bertrand, Walker, Caput, Graham, Bertrand, Besnard: "A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit." in: Molecular pharmacology, Vol. 61, Issue 1, pp. 150-9, (2001) (PubMed).

    Nguyen, Ndoye, Grando: "Novel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunity." in: The American journal of pathology, Vol. 157, Issue 4, pp. 1377-91, (2000) (PubMed).

  • 抗原
    CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
    别名
    CHRNA9 (CHRNA9 产品)
    别名
    HSA243342 antibody, NACHRA9 antibody, 2410015I05Rik antibody, Acra9 antibody, EG666827 antibody, Gm8311 antibody, cholinergic receptor nicotinic alpha 9 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 9 antibody, CHRNA9 antibody, Chrna9 antibody
    背景
    Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.
    分子量
    54807
    基因ID
    55584
    UniProt
    Q9UGM1
    途径
    Sensory Perception of Sound
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