CHRNA9 抗体 (N-Term)
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Quick Overview for CHRNA9 抗体 (N-Term) (ABIN2792251)
抗原
See all CHRNA9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CHRNA9 Antibody - N-terminal region
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序列
- MNWSHSCISF CWIYFAASRL RAAETADGKY AQKLFNDLFE DYSNALRPVE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 93%, Rabbit: 100%, Zebrafish: 80%
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产品特性
- This is a rabbit polyclonal antibody against CHRNA9. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA9
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).
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- CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
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别名
- CHRNA9
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背景
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Targeted Subunit: alpha-9
Background Information: CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
Gene Name: Cholinergic receptor, nicotinic, alpha 9 (neuronal)
Alternative Symbols: NACHRA9, HSA243342
Protein Name: Neuronal acetylcholine receptor subunit alpha-9
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分子量
- 55 kDa
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基因ID
- 55584
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NCBI登录号
- NP_060051
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UniProt
- Q9UGM1
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途径
- Sensory Perception of Sound
抗原
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