SPG11 抗体
SPG11
适用: 人, 小鼠, 大鼠
ELISA, WB, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SPG11 抗体
- SPG11 (Spastic Paraplegia 11 (Autosomal Recessive) (SPG11))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPG11 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 15 amino acid peptide of human SPG11.
- Top Product
- Discover our top product SPG11 Primary Antibody
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anti-Spastic Paraplegia 11 (Autosomal Recessive) (SPG11) (AA 2019-2318) antibody
SPG11 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Paraplegia 11 (Autosomal Recessive) (SPG11) (AA 1-425) antibodySPG11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- SPG11 (Spastic Paraplegia 11 (Autosomal Recessive) (SPG11))
- 别名
- SPG11 (SPG11 产品)
- 别名
- 6030465E24Rik antibody, A330015I11 antibody, C530005A01Rik antibody, KIAA1840 antibody, RGD1562529 antibody, SPG11, spatacsin vesicle trafficking associated antibody, Spg11 antibody, SPG11 antibody
- 背景
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Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.? Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration.Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC.Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage.It is expressed in all structures of the brain, with a high expression in the cerebellum.SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC.Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene.? Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.
Synonyms: Spastic paraplegia 11, colorectal carcinoma-associated protein, spatacsin
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