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NLRP12 抗体 (N-Term)

NLRP12 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1888171
发货至: 中国
  • 抗原 See all NLRP12 抗体
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 51
    • 18
    • 15
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 3
    • 1
    克隆类型
    • 51
    • 3
    多克隆
    标记
    • 20
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP12 antibody is un-conjugated
    应用范围
    • 37
    • 33
    • 14
    • 13
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    NALP12 antibody was raised against an 18 amino acid peptide near the amino terminus of human NALP12.
    Top Product
    Discover our top product NLRP12 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    别名
    NALP12 (NLRP12 产品)
    别名
    Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
    背景
    NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction.Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain.NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kappaB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes.Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
    Synonyms: NACHT, LRR and PYD domains-containing protein 12, NLRP12, FCAS2, CLR19.3, PAN6, PYPAF7, RNO, RNO2, Monarch-1
    NCBI登录号
    NP_653288
    途径
    Positive Regulation of Endopeptidase Activity, Inflammasome
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