NLRP12 抗体 (N-Term)
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- 抗原 See all NLRP12 抗体
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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抗原表位
- AA 183-212, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NLRP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-212 amino acids from the N-terminal region of human NLRP12.
- 克隆位点
- RB33963
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NLRP12 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- NLRP12 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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NLRP12 modulates host defense through IL-17A-CXCL1 axis." in: Mucosal immunology, (2015) (PubMed).
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NLRP12 modulates host defense through IL-17A-CXCL1 axis." in: Mucosal immunology, (2015) (PubMed).
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- 抗原
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
- 别名
- NLRP12 (NLRP12 产品)
- 别名
- Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
- 背景
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
- 分子量
- 120173
- 基因ID
- 91662
- NCBI登录号
- NP_001264055, NP_001264058, NP_653288
- UniProt
- P59046
- 途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
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