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ATP2C2 抗体 (N-Term)

ATP2C2 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1888109
发货至: 中国
  • 抗原 See all ATP2C2 抗体
    ATP2C2 (ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2))
    抗原表位
    • 4
    • 2
    • 1
    N-Term
    适用
    人, 小鼠
    宿主
    • 7
    克隆类型
    • 8
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    This ATP2C2 antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应 (详细)
    At least three isoforms of ATP2C2 are known to exist. ATP2C2 antibody will not cross-react with ATP2C1
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    19 amino acid peptide near the amino terminus of human ATP2C2.
    Top Product
    Discover our top product ATP2C2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    ATP2C2 (ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2))
    别名
    ATP2C2 (ATP2C2 产品)
    别名
    KIAA0703 antibody, MGC146612 antibody, SPCA2 antibody, 1810010G06Rik antibody, Spca2 antibody, mKIAA0703 antibody, ATPase secretory pathway Ca2+ transporting 2 antibody, ATPase, Ca++ transporting, type 2C, member 2 S homeolog antibody, ATPase, Ca++ transporting, type 2C, member 2 antibody, ATP2C2 antibody, atp2c2.S antibody, atp2c2 antibody, Atp2c2 antibody
    背景
    ATP2C2, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 2, belongs to the family of P-type cation transport ATPases.This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen.Defects in the related gene ATP2C1 cause Hailey-Hailey disease, for which ATP2C2 does not compensate, suggesting that ATP2C2 plays other physiological roles.Unlike ATP2C1, ATP2C2 has a much more restricted expression pattern and displays a higher maximal turnover rate for overall Ca2+-ATPase reaction and a lower apparent affinity for cytosolic Ca2+ activation of phosphorylation.Overexpression of ATP2C2 in mammary tumors result a Ca2+ influx via the store-operated Ca2+ channel ORAI1 and independent of the STIM1 and STIM2 sensors.
    Synonyms: Calcium-transporting ATPase type 2C member 2, PMR1, SPCA2, hSPCA2
    NCBI登录号
    NP_055676
    途径
    Ribonucleoside Biosynthetic Process
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