ATP2C2 抗体 (N-Term)
ATP2C2
适用: 人, 小鼠
ELISA, WB, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all ATP2C2 抗体
- ATP2C2 (ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP2C2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- At least three isoforms of ATP2C2 are known to exist. ATP2C2 antibody will not cross-react with ATP2C1
- 纯化方法
- ATP2C2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ATP2C2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP2C2. The immunogen is located within the first 50 amino acids of ATP2C2.
- 亚型
- IgG
- Top Product
- Discover our top product ATP2C2 Primary Antibody
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anti-ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2) (AA 621-702) antibody
ATP2C2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2) (N-Term) antibodyATP2C2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ATP2C2 antibody can be used for detection of ATP2C2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ATP2C2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ATP2C2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- ATP2C2 (ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2))
- 别名
- ATP2C2 (ATP2C2 产品)
- 别名
- KIAA0703 antibody, MGC146612 antibody, SPCA2 antibody, 1810010G06Rik antibody, Spca2 antibody, mKIAA0703 antibody, ATPase secretory pathway Ca2+ transporting 2 antibody, ATPase, Ca++ transporting, type 2C, member 2 S homeolog antibody, ATPase, Ca++ transporting, type 2C, member 2 antibody, ATP2C2 antibody, atp2c2.S antibody, atp2c2 antibody, Atp2c2 antibody
- 背景
- ATP2C2 Antibody: ATP2C2, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 2, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in the related gene ATP2C1 cause Hailey-Hailey disease, for which ATP2C2 does not compensate, suggesting that ATP2C2 plays other physiological roles. Unlike ATP2C1, ATP2C2 has a much more restricted expression pattern and displays a higher maximal turnover rate for overall Ca2+-ATPase reaction and a lower apparent affinity for cytosolic Ca2+ activation of phosphorylation. Overexpression of ATP2C2 in mammary tumors result a Ca2+ influx via the store-operated Ca2+ channel ORAI1 and independent of the STIM1 and STIM2 sensors.
- 基因ID
- 9914
- NCBI登录号
- NP_055676
- UniProt
- O75185
- 途径
- Ribonucleoside Biosynthetic Process
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