UNC93B1 抗体 (N-Term)
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- 抗原 See all UNC93B1 抗体
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UNC93B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应 （详细）
- Multiple isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93a.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid peptide from near the amino terminus of human Unc93b.
- Top Product
- Discover our top product UNC93B1 Primary Antibody
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anti-Unc-93 Homolog B1 (UNC93B1) (AA 451-550) antibody
UNC93B1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 83-135) antibodyUNC93B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 500-550) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 61-110) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 450-550) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 300-597) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
- 别名
- Unc93b (UNC93B1 产品)
- 别名
- UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody
- 背景
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The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C.elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling.Unlike Unc93a, another homolog of the C.elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9, the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction.Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indicating that Unc93b plays an important role in innate immunity.
Synonyms: Unc93b1, homolog of C.elegans Unc93 - 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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