SIPA1L1 抗体 (N-Term)
SIPA1L1
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SIPA1L1 抗体
- SIPA1L1 (Signal-Induced Proliferation-Associated 1 Like 1 (SIPA1L1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIPA1L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid peptide from near the amino terminus of human SIPA1L1.
- Top Product
- Discover our top product SIPA1L1 Primary Antibody
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anti-Signal-Induced Proliferation-Associated 1 Like 1 (SIPA1L1) (N-Term) antibody
SIPA1L1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- SIPA1L1 (Signal-Induced Proliferation-Associated 1 Like 1 (SIPA1L1))
- 别名
- SIPA1L1 (SIPA1L1 产品)
- 别名
- 4931426N11Rik antibody, AW213287 antibody, Spar antibody, mKIAA0440 antibody, SPAL antibody, Spa-1 antibody, Spa1 antibody, E6TP1 antibody, cb600 antibody, id:ibd5092 antibody, sb:cb600 antibody, si:ch211-106p8.1 antibody, wu:fc43g06 antibody, signal induced proliferation associated 1 like 1 antibody, signal-induced proliferation-associated 1 like 1 antibody, SIPA1L1 antibody, sipa1l1 antibody, Sipa1l1 antibody
- 背景
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Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs.SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses.Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1.CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.
Synonyms: Signal-induced proliferation associated-like protein 1, E6TP1 - NCBI登录号
- NP_056371
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