SIPA1L1 抗体 (N-Term)
SIPA1L1
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SIPA1L1 抗体
- SIPA1L1 (Signal-Induced Proliferation-Associated 1 Like 1 (SIPA1L1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIPA1L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- SIPA1L1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human SIPA1L1.
- 亚型
- IgG
- Top Product
- Discover our top product SIPA1L1 Primary Antibody
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- SIPA1L1 (Signal-Induced Proliferation-Associated 1 Like 1 (SIPA1L1))
- 别名
- SIPA1L1 (SIPA1L1 产品)
- 别名
- 4931426N11Rik antibody, AW213287 antibody, Spar antibody, mKIAA0440 antibody, SPAL antibody, Spa-1 antibody, Spa1 antibody, E6TP1 antibody, cb600 antibody, id:ibd5092 antibody, sb:cb600 antibody, si:ch211-106p8.1 antibody, wu:fc43g06 antibody, signal induced proliferation associated 1 like 1 antibody, signal-induced proliferation-associated 1 like 1 antibody, SIPA1L1 antibody, sipa1l1 antibody, Sipa1l1 antibody
- 背景
- Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.Synonyms: E6-targeted protein 1, E6TP1, KIAA0440, SIPA1-like protein 1, Signal-induced proliferation-associated 1-like protein 1
- 基因ID
- 26037
- NCBI登录号
- NP_056371
- UniProt
- O43166
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