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DACT2 抗体 (N-Term)

DACT2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887827
发货至: 中国
  • 抗原 See all DACT2 抗体
    DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))
    抗原表位
    • 2
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This DACT2 antibody is un-conjugated
    应用范围
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    12 amino acid peptide from near the amino terminus of human DACT2.
    Top Product
    Discover our top product DACT2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))
    别名
    Dact2 (DACT2 产品)
    别名
    2900084M21Rik antibody, A630024E20 antibody, Dpr2 antibody, Frd2 antibody, dapper2 antibody, C6orf116 antibody, DAPPER2 antibody, DPR2 antibody, RP11-503C24.7 antibody, bA503C24.7 antibody, dishevelled binding antagonist of beta catenin 2 antibody, dishevelled-binding antagonist of beta-catenin 2 antibody, DACT2 antibody, Dact2 antibody
    背景
    The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases.Many members of this pathway are also expressed in the postnatal tissues such as brain.One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling.Dact2 is most prominent during the development of the thymus kidneys, and salivary gland.Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling.Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors.At least two isoforms of Dact2 are known to exist.
    Synonyms: Dapper homolog 2, Dapper antagonist of beta-catenin 2
    NCBI登录号
    NP_999627
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