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DACT2 抗体 (N-Term)

DACT2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991002
发货至: 中国
  • 抗原 See all DACT2 抗体
    DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))
    抗原表位
    AA 150-200, N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This DACT2 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    Dact2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Dact2 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human DACT2. The immunogen is located within amino acids 150 - 200 of Dact2.
    亚型
    IgG
    Top Product
    Discover our top product DACT2 Primary Antibody
  • 应用备注
    Dact2 antibody can be used for detection of Dact2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Dact2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Dact2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))
    别名
    Dact2 (DACT2 产品)
    别名
    2900084M21Rik antibody, A630024E20 antibody, Dpr2 antibody, Frd2 antibody, dapper2 antibody, C6orf116 antibody, DAPPER2 antibody, DPR2 antibody, RP11-503C24.7 antibody, bA503C24.7 antibody, dishevelled binding antagonist of beta catenin 2 antibody, dishevelled-binding antagonist of beta-catenin 2 antibody, DACT2 antibody, Dact2 antibody
    背景
    Dact2 Antibody: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact2 is most prominent during the development of the thymus kidneys, and salivary gland. Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling. Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors. At least two isoforms of Dact2 are known to exist.
    基因ID
    168002
    NCBI登录号
    NP_999627
    UniProt
    Q5SW24
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