Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (Middle Region) 抗体
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- 抗原 See all Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) 抗体
- Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)
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抗原表位
- Middle Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Ion exchange chromatography purified
- 免疫原
- Peptide corresponding to 14 amino acids near the middle of human NADE.
- Top Product
- Discover our top product NGFRAP1 Primary Antibody
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anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (Center) antibody
NGFRAP1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 1-111) antibodyNGFRAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 1-101) antibodyNGFRAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 1-110) antibodyNGFRAP1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 1-111) antibodyNGFRAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (Middle Region) antibodyNGFRAP1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)
- 别名
- NADE (NGFRAP1 产品)
- 别名
- BEX3 antibody, Bex antibody, DXS6984E antibody, HGR74 antibody, NADE antibody, NGFRAP1 antibody, LNGFR antibody, Tnfrsf16 antibody, p75 antibody, p75NGFR antibody, p75NTR antibody, AL033356 antibody, Bex3 antibody, DXWsu67e antibody, Gcap27 antibody, Nade antibody, WBP5 antibody, brain expressed X-linked 3 antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, BEX3 antibody, Ngfr antibody, Bex3 antibody
- 背景
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The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF).The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR.Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac).Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization.It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed.Finally, although initially discovered as an mRNA expressed in ovarian granulosa cells, NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage.
- NCBI登录号
- NP_996798
- 途径
- Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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