NPAS3 抗体 (Center)
NPAS3
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all NPAS3 抗体
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPAS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 28 amino acid peptide from near the center of human NPAS3.
- Top Product
- Discover our top product NPAS3 Primary Antibody
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anti-Neuronal PAS Domain Protein 3 (NPAS3) (N-Term) antibody
NPAS3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Neuronal PAS Domain Protein 3 (NPAS3) (Middle Region) antibodyNPAS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 山羊, 斑马鱼, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
- 别名
- NPAS3 (NPAS3 产品)
- 别名
- trh antibody, mop6 antibody, pasd6 antibody, MGC145768 antibody, MOP6 antibody, PASD6 antibody, bHLHe12 antibody, 4930423H22Rik antibody, neuronal PAS domain protein 3 antibody, npas3 antibody, NPAS3 antibody, Npas3 antibody
- 背景
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Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia.It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region.NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities.Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin.These results demonstrate the essential role played by NPAS3 during structural and functional brain development.At least three isoforms of NPAS3 are known to exist.
Synonyms: Neuronal PAS domain-containing protein 3, member of Pas protein 6, MOP6 - UniProt
- Q8IXF0
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