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Prostaglandin D2 Receptor 2 (PTGDR2) (Center) 抗体

PTGDR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887538
发货至: 中国
  • 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
    Prostaglandin D2 Receptor 2 (PTGDR2)
    抗原表位
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    Center
    适用
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    非结合性
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide from near the center of human CRTH2.
    Top Product
    Discover our top product PTGDR2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    Prostaglandin D2 Receptor 2 (PTGDR2)
    别名
    CRTH2 (PTGDR2 产品)
    别名
    CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
    背景
    The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor.CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses.However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3.This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.At least two different isoforms of CRTH2 are known to exist.
    Synonyms: Chemoattractant receptor-homologous molecule expressed on Th2 cells, GPR44
    NCBI登录号
    NP_004769
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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