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ECSIT 抗体 (C-Term)

ECSIT 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887360
发货至: 中国
  • 抗原 See all ECSIT 抗体
    ECSIT
    抗原表位
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 23
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This ECSIT antibody is un-conjugated
    应用范围
    • 23
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Ion exchange chromatography purified
    免疫原
    Peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.
    Top Product
    Discover our top product ECSIT Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    ECSIT
    别名
    ECSIT (ECSIT 产品)
    别名
    CG10610 antibody, DmECSIT antibody, Dmel\\CG10610 antibody, dECSIT antibody, ECSIT antibody, Sitpec antibody, SITPEC antibody, CG10610 gene product from transcript CG10610-RA antibody, ECSIT signalling integrator antibody, ecsit antibody, ECSIT signalling integrator S homeolog antibody, ECSIT antibody, CpipJ_CPIJ003637 antibody, Ecsit antibody, ecsit.S antibody
    背景
    Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses.Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6.ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway.Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
    NCBI登录号
    NP_057665
    途径
    TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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