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ZFYVE26 抗体 (C-Term)

ZFYVE26 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887150
发货至: 中国
  • 抗原 See all ZFYVE26 抗体
    ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 11
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    克隆类型
    • 11
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    This ZFYVE26 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide near the carboxy terminus of human SPG15.
    Top Product
    Discover our top product ZFYVE26 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))
    别名
    SPG15 (ZFYVE26 产品)
    别名
    wu:fc33a03 antibody, FYVE-CENT antibody, SPG15 antibody, 4930465A13 antibody, 9330197E15Rik antibody, A630028O16Rik antibody, Gm893 antibody, mKIAA0321 antibody, zinc finger, FYVE domain containing 26 antibody, zinc finger FYVE-type containing 26 antibody, zfyve26 antibody, ZFYVE26 antibody, Zfyve26 antibody
    背景
    Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.? Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration.SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population.Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane.SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development.SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking.Multiple isoforms of SPG15 are known to exist.
    Synonyms: Autosomal recessive spastic paraplegia 15, ZFYVE26
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