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ZFYVE26 抗体 (C-Term)

ZFYVE26 适用: 人, 小鼠, 大鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991064
发货至: 中国
  • 抗原 See all ZFYVE26 抗体
    ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 1710-1760, C-Term
    适用
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 6
    • 2
    • 1
    • 1
    This ZFYVE26 antibody is un-conjugated
    应用范围
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Multiple isoforms of SPG15 are known to exist.
    纯化方法
    SPG15 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SPG15 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SPG15. The immunogen is located within amino acids 1710 - 1760 of SPG15.
    亚型
    IgG
    Top Product
    Discover our top product ZFYVE26 Primary Antibody
  • 应用备注
    SPG15 antibody can be used for detection of SPG15 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SPG15 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SPG15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))
    别名
    SPG15 (ZFYVE26 产品)
    别名
    wu:fc33a03 antibody, FYVE-CENT antibody, SPG15 antibody, 4930465A13 antibody, 9330197E15Rik antibody, A630028O16Rik antibody, Gm893 antibody, mKIAA0321 antibody, zinc finger, FYVE domain containing 26 antibody, zinc finger FYVE-type containing 26 antibody, zfyve26 antibody, ZFYVE26 antibody, Zfyve26 antibody
    背景
    SPG15 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.  Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development. SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking.
    分子量
    Predicted: 280 kDa

    Observed: 260 kDa
    基因ID
    23503
    UniProt
    Q68DK2
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