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Beclin 1 抗体 (C-Term)

BECN1 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887089
发货至: 中国
  • 抗原 See all Beclin 1 (BECN1) 抗体
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    抗原表位
    • 16
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    • 9
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    • 9
    • 8
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 192
    • 86
    • 71
    • 9
    • 8
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    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 162
    • 33
    • 2
    克隆类型
    • 163
    • 34
    多克隆
    标记
    • 87
    • 17
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    • 13
    • 13
    • 4
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    • 4
    • 2
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    • 1
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    This Beclin 1 antibody is un-conjugated
    应用范围
    • 137
    • 94
    • 55
    • 34
    • 26
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    • 17
    • 13
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide from near the carboxy terminus of human Beclin-1.
    Top Product
    Discover our top product BECN1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    别名
    Beclin-1 (BECN1 产品)
    别名
    beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.Beclin-1, a coiled-coil Bcl-2-interacting protein homologous to the yeast autophagy gene apg6, is a mammalian autophagy gene that can inhibit tumorigenesis and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors.Bcl-2 can bind to Beclin-1 and inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as an anti-autophagy protein as well as an anti-apoptotic protein, which helps maintain autophagy at levels that are more compatible with cell survival rather than cell death.
    Synonyms: Coiled-coil myosin-like Bcl-2-interacting protein
    途径
    Autophagy
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