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ATF6 抗体 (C-Term)

ATF6 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887087
发货至: 中国
  • 抗原 See all ATF6 抗体
    ATF6 (Activating Transcription Factor 6 (ATF6))
    抗原表位
    • 16
    • 15
    • 11
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 81
    • 43
    • 32
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 71
    • 10
    • 1
    克隆类型
    • 74
    • 8
    多克隆
    标记
    • 43
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ATF6 antibody is un-conjugated
    应用范围
    • 73
    • 27
    • 27
    • 24
    • 15
    • 15
    • 15
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide from near the carboxy terminus of human ATF6.
    Top Product
    Discover our top product ATF6 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    ATF6 (Activating Transcription Factor 6 (ATF6))
    别名
    ATF6 (ATF6 产品)
    别名
    ATF-6-like antibody, GB16435 antibody, ATF6 antibody, Atf6 antibody, ATF6A antibody, 9130025P16Rik antibody, 9630036G24 antibody, AA789574 antibody, Atf6alpha antibody, ESTM49 antibody, activating transcription factor 6 antibody, uncharacterized LOC412432 antibody, activating transcription factor 6 S homeolog antibody, cyclic AMP-dependent transcription factor ATF-6 alpha antibody, ATF6 antibody, LOC412432 antibody, atf6.S antibody, LOC100122162 antibody, Atf6 antibody
    背景
    Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus.Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR.ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes.ATF6 has two isoforms (ATF6alpha and ATF6beta), only ATF6alpha is recognized by this antibody.
    Synonyms: Activating transcription factor 6
    NCBI登录号
    NP_031374
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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