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CD82 抗体 (C-Term)

CD82 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887018
发货至: 中国
  • 抗原 See all CD82 抗体
    CD82
    抗原表位
    • 15
    • 9
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 36
    • 6
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 54
    • 25
    克隆类型
    • 53
    • 26
    多克隆
    标记
    • 29
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD82 antibody is un-conjugated
    应用范围
    • 52
    • 31
    • 22
    • 20
    • 19
    • 18
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide from near the carboxy terminus of human KAI1.
    Top Product
    Discover our top product CD82 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    CD82
    别名
    KAI1 (CD82 产品)
    别名
    AA682076 antibody, AL023070 antibody, C33 antibody, IA4 antibody, Kai1 antibody, Tspan27 antibody, 4F9 antibody, GR15 antibody, KAI1 antibody, R2 antibody, SAR2 antibody, ST6 antibody, TSPAN27 antibody, CD82 antigen antibody, CD82 molecule antibody, Cd82 molecule antibody, Cd82 antibody, CD82 antibody
    背景
    KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene.This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression.The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients.Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen.It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases.At least two isoforms of KAI1 are known to exist.
    Synonyms: CD82 antigen, tetraspanin-27, Tspan-27, suppressor of tumorgenicity-6
    NCBI登录号
    NP_002222
    途径
    p53 Pathway
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