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MANF 抗体 (C-Term)

MANF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886911
发货至: 中国
  • 抗原 See all MANF 抗体
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    • 8
    • 1
    克隆类型
    • 41
    • 6
    多克隆
    标记
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MANF antibody is un-conjugated
    应用范围
    • 39
    • 24
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    This antibody does not cross-react with CDNF.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    12 amino acid peptide from near the carboxy terminus of human MANF.
    Top Product
    Discover our top product MANF Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    别名
    MANF (MANF 产品)
    别名
    ARMET antibody, ARP antibody, 3230402M22Rik antibody, AA407711 antibody, AA408789 antibody, AA673178 antibody, Armet antibody, D17914 antibody, D18Mgi17 antibody, MANF antibody, RBM15B antibody, ARP-like antibody, CG7013 antibody, DmMANF antibody, Dmel\\CG7013 antibody, anon-EST:ParkEST188 antibody, arp antibody, armet antibody, im:6909481 antibody, zgc:153327 antibody, manf antibody, mesencephalic astrocyte derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor antibody, RNA binding motif protein 15B antibody, Mesencephalic astrocyte-derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor S homeolog antibody, MANF antibody, Manf antibody, RBM15B antibody, manf antibody, manf.S antibody
    背景
    MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors.More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF.In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release.Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease.Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.
    Synonyms: Mesencephalic astrocyte-derived neurotrophic factor, arginine-rich mutatedin early stage tumor, ARMET, ARP
    UniProt
    P55145
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