DIABLO 抗体 (AA 225-239)
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北京 101111
Quick Overview for DIABLO 抗体 (AA 225-239) (ABIN1886859)
抗原
See all DIABLO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-239
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Peptide corresponding to amino acids 225 to 239 of human Smac/DIABLO.
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anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibody
DIABLO 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 211-239), (C-Term) antibodyDIABLO 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20755 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 79-1-83 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyKD Validated DIABLO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2575 unconjugated Recombinant Antibody
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibodyDIABLO 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal AT19F2 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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别名
- Smac
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背景
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The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes.A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO.Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway.Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases.Smac/DIABLO is expressed in a variety of human and mouse tissues.
Synonyms: DIABLO -
分子量
- 25 kDa
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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