Retinoblastoma Binding Protein 8 抗体 (AA 452-747)
Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 452-747) (ABIN1886481)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 452-747
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 452 and 747 of CtIP
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- Retinoblastoma Binding Protein 8 (RBBP8)
-
别名
- CtIP
-
背景
-
The protein encoded by this gene is a ubiquitously expressed nuclear protein.It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation.This protein complexes with transcriptional co-repressor CTBP.It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1.Three transcript variants encoding two different isoforms have been found for this gene.More transcript variants exist, but their full-length natures have not been determined.[provided by RefSeq]
-
分子量
- 102 kDa
-
基因ID
- 5932
-
NCBI登录号
- NM_002894, NP_002885
-
途径
- Cell Division Cycle, DNA Damage Repair
抗原
-